Oswestry Keele Orthopaedic Research group

Last updated on Nov 1, 2023 Equipment

Fluostar Omega Plate Reader

Funded by “Higher Education Funding Council for England”

Charlotte Hulme, Heidi Fuller, Sally Roberts, Peter Gallacher, Karina Wright

Last updated on Nov 1, 2023

Biomarker discovery in orthopaedics: Matching patients to the best treatment

Funded by Versus Arthritis

Helen McCarthy, Iain McCall, Claire Mennan, Mike Williams, James Richardson, Sally Roberts

Last updated on Nov 1, 2023

Prediction of clinical outcome following ACI by magnetic resonance imaging

Funded by Versus Arthritis and the UKRI

Karina Wright, Charlotte Hulme, Paul Cool, Mateus Harrington, Jessica Fisher-Stokes

Last updated on Nov 1, 2023

Biomarkers and prognostic modelling in SCI using proteomics, bioinformatics and in vitro models

Funded by the EPSRC (UKRI)

Last updated on Jun 19, 2024 Events

Charity events

Last updated on Jun 19, 2024 Events

EULAR congress

Oksana Kehoe, Rebecca Davies, Anaïs Makos, Henry Barrett

Last updated on Dec 30, 2024 Events

Extracellular vesicle events

Martyn Snow, Pete Gallacher, Paul Jermin, Karina Wright, Charlotte Hulmes, Jade Perry, Timothy Hopkins, Larissa Rix, Tian Lan

Last updated on Jun 19, 2024 Events

ICRS

Oksana Kehoe, Charlotte Hulme, Larissa Rix, Rebecca Davis, Anaïs Makos, Tian Lan, Jessica Fisher-Stokes

Last updated on Jun 19, 2024 Events

Keele courses and conferences

Last updated on Jun 19, 2024 Events

Outreach event

Oksana Kehoe, Karina Wright, Jan Herman Kuiper, Charlotte Hulmes, Jade Perry, Helen McCarthy, Claire Mennan, Timothy Hopkins, Lauren Tierney, Rebecca Davis, Anaïs Makos, Tian Lan, Jessica Fisher-Stokes, John Garcia, Abi Jones, Hollie Wilkinson, Tom Link, Yumna Ladha

Last updated on Jun 19, 2024 Events

Research Day

Nicola Kuiper, Charlotte Hume, Oksana Kehoe, Mike Williams, Karina Wright

Last updated on Jan 15, 2024

Does knee cartilage repair surgery prevent arthritis or the need for a joint replacement?

Funded by the Daphne Jackson Trust, the Orthopaedic Research UK and the Medical Research Council

Karina Wright, Martyn Snow

Last updated on Nov 1, 2023

Advancing Osteochondral Tissue Supply Chain Transport Conditions for Clinical Allografts

Funded

Karina Wright, Paul Cool, Helen McCarthy, Jade Perry, Hollie Wilkinson

Last updated on Nov 1, 2023

Artificial Intelligence in the diagnosis of orthopaedic conditions (Bone Tumours and Infection)

Funded by the RJAH Orthopaedic and District…

Henry Barrett, Oksana Kehoe, C. Hulmes, L. Smyth, M.A De Lima, A. Clayton, N. Telling, R. Amarasena

Last updated on Nov 1, 2023

The potential utility of human regulatory T cell-derived EV to control inflammation in RA

Funded by the Orthopaedic Institute and Kee…

Karina Wright, Helen McCarthy, Charlotte Hulme, Jan Kuiper, Martyn Snow, Abi Jones

Last updated on Nov 1, 2023

Transcriptomic, proteomic and bioinformatics analyses of cell-based therapies

Funded by Versus arthritis

Last updated on Nov 1, 2023 Equipment

Agilent tape station

Funded by the Orthopaedic Institute

Last updated on Nov 1, 2023 Equipment

Epredia HM525 NX Cryostat

Funded by the Orthopaedic Institute

Last updated on Nov 1, 2023 Equipment

Mirus Ingento Ezporator

Last updated on Nov 1, 2023 Equipment

Terumo BCT Quantum Cell Expansion System

Rebecca Davies, Mairead Hyland, Claire Mennan, Karina Wright, Mark Platt, Oksana Kehoe

Last updated on Nov 1, 2023

MSCs-Derived Extracellular Vesicles Attenuate Disease Severity in Inflammatory Arthritis

Funded by the Orthopaedic Institute and K…

Jones F, Stefan A, Kay A, Mairead Hyland, Morgan R, Forsyth N, Pisconti A, Oksana Kehoe

Last updated on Nov 1, 2023

Syndecan-3 plays a role in MSC adhesion and efficacy in an in vivo model of inflammatory arthritis

Funded by the EPSRC & MRC, Oswestry Rheu…

Garcia J, Roberts S, Tins B, Jermin P, Gallacher P, Kehoe O, Wright K, Stewart C, Kuiper JH

Last updated on Nov 1, 2023

A 12-month clinical study. Spontaneous healing of articular cartilage (SHARC study)

Funded by the Medical Research Council (UKRI)

John Garcia, Charlotte Hulme, Claire Mennan, Sally Roberts, Karina Wright

Last updated on Nov 1, 2023

Human chondrocytes expanded in the Quantum® hollow-fibre bioreactor system

Funded by the MRC (UKRI) and Versus Arthritis

Jade Perry, Helen McCarthy, Sally Roberts, Jermin P, Gallacher P, Richardson J, Williams M, Tins B

Last updated on Nov 1, 2023

The suitability of pre-operative MRI in predicting accurate cartilage defect sizes in cell therapy

Funded by Versus Arthritis and Keele University

Jingsong Wang, Sally Roberts, Bernhard Tins, James Richardson, Karina Wright

Last updated on Nov 1, 2023

Tissue engineering of meniscus cells, bmscs, chondrocytes and co-cultures on a scaffolds

Funded by the Orthopaedic Institute

Timothy Hopkins, Karina Wright, Sally Roberts, Nicola Kuiper, Jan Herman Kuiper

Last updated on Nov 1, 2023

Biological, physical and psychosocial factors that affect the health of the human knee

Funded by the Orthopaedic Institute

Perry J, Mennan C, McCarthy H, Bou-Gharios G, Van'T Hof R, Milner P, De Bari C, Wright K, Roberts S

Last updated on Nov 1, 2023

Can cells from umbilical cords be used to treat patients with osteoarthritis?

Funded by Versus Arthritis and Keele University

Claire Mennan, Helen McCarthy, Daniel Tonge, Sally Roberts

Last updated on Nov 1, 2023

Transcriptome analysis of the umbilical cord-MSCs' therapeutic response to inflammation

Funded by Versus Arthritis and the Orthopaed…

Tian Lan, Charlotte Hulme, Helen McCarthy, Karina Wright, Nilesh Makwana, Andrew Bing

Last updated on Nov 1, 2023

Cell therapy for repair of cartilage defects in the ankle - how does it work and who should we treat?

Funded by the Orthopaedic Institute

Anaïs Makos, Jan Herman Kuiper, Roshan Amarasena, Oksana Keohe

Last updated on Nov 1, 2023

Biomarkers for the PARIS study: Psoriatic Arthritis - Resistance to TNF Inhibitor Study

Funded by the RJAH Hospital Charitable Fund

Rebecca Davies, Mairead Hyland, Claire Mennan, Karina Wright, Mark Platt, Oksana Kehoe

Last updated on Nov 1, 2023

Up-scaling UC-MSC extracellular vesicle production for rheumatoid arthritis treatment

Funded by James Richardson Studentship, Ort…

Projects