I am a first year PhD student with Keele university. I am based at the Robert Jones and Agnes Hunt Orthopaedic hospital, Oswestry. My project aims to compare Treg-derived extracellular vesicles (EV) from rheumatoid arthritis (RA) patients to healthy donors.

Current Treatments for autoimmune disorders like RA can be poorly tolerated, ineffective, and lead to the development of opportunistic infections. Comparing the different immuno-suppressive efficacies of healthy and RA EVs will allow us to explore their therapeutic potential and guide our approach to manufacturing for clinical use. Additionally, identifying differentially expressed vesicular factors could help improve our understanding of the mechanisms that underpin RA, potentially leading to improved diagnostics and tailoring of treatment regimes.